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Counter effects of omega 3 fatty acid and vitamin E on action of paxil.

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I have recently started taking paxil for a serious anxiety disorder and I am worried about gaining weight. I am already slightly overweight and naturally I would prefer to not gain any more. My question is about omega 3 and vitamin e. I read that taking these supplements while on paxil help to counter the effects of the paxil weight gain. Without stating the obvious about exercise and and a healthy diet could you please inform me whether or not studies have show this to actually be true or if it is just more homeopathic fanfare made popular by soccer mom gossip?

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Dr. John Monheit
Category: Family Physician-GP
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Expert:  Dr. John Monheit
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HI,

There a few researches that have confirmed that vitamin E and in particular omega 3 fatty acid reduces the weight gain associated with paxil. Although the mechanism is not clear, it is more likely due to the decreases metabolism of fat that occurs with their intake. Omega 3 fatty acid, also counter acts the atherogenesis of vessels and decreases the chances of heart attacks in people taking paxil.

I would recommend that you meet you doctor and discuss with him some other medications that have the same efficacy as praxil to treat depression but have decreased weight gain and sexual side effects. These drugs are FDA approved and available in the market.

Vitamin E and omega fatty acids are effective but they do have their share of side effects. They are associated with abdominal pain and change in stool consistency. Fish oils can cause bad breath.

Thank you.

Dr. John Monheit
Category: Family Physician-GP
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Residecny: North Colorado Family Medicine
Medical School: The Chicago Medical Center
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