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Chances of ER positive LOBULAR CANCER with ALLRED score8.

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I have very very ER positive lobular cancer. I had 8 lymph nodes so I worry about it spreading though. I want to be able to trust the AI therapy, but I worry that if the cells mutate, they may become ER negative. My ALLRED score is 8. Is it likely for someone with such indolent breast cancer to have it change to ER- when it divides? I am hoping that slow divisions help avoid mistakes (such as an ER positive cancer turning ER negative). What do you think? What do you think the chances are of any divisions keeping the ER positive status?

Category: Oncologist

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Dr. Prasad Eswaran
Category: Hematologist
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Expert:  Dr. Prasad Eswaran
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Dear
ER positivity of Allred 8 has an ecellent prognosis. The chances of mutation to become ER negative takes probably a very long time, in years, though definitive number cannot be determined.


Patient replied :

Thank you. Are you sure that breast cancers with high ALLRED scores are more indolent than other cancers? Do you have any proof of this?


Expert:  Dr. Prasad Eswaran
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The proof for good prognosis in high ALLRED score is all over the internet and scientific literature.
Regards

Dr. Prasad Eswaran
Category: Hematologist
Experience: 
Doctorate in Medicine (Fellowship in Oncology), DM,  Madras Medical College & Govt. General Hospital, Chennai, India.

Doctor of Medicine (Residency in Radiation Oncology) , MD, Christian Medical College, Vellore, Tamilnadu, India, 2004-06.

Diploma in Medical Radiology & Therapy (Residency in Radiation Oncology), D.M.R.T, Madras Medical College & Govt. General Hospital, Chennai, India, 2004-06.

Bachelor of Medicine & Bachelor of Surgery - M.B.B.S, Govt. Stanley Medical College & Hospital, Chennai, India, 1998-2004.
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