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NON DRUG INDUCED LUPUS-LIKE SYNDROME.Is there a thing?

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Is there such a thing as NON drug-induced lupus-like syndrome.

Category: Family Physician-GP

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Category: HIV- AIDS Specialist
 28 Doctors Online

Hello,
Thank you for your query at DoctorSpring.com
No there is no such entity called non drug induced Lupus.
The lupus like reaction or drug induced lupus ( DIL ) can only occur when certain drugs such as Hydralazine or Procainamide are consumed. Mainly the reaction takes place due to differences in drug metabolism and acetylation.
The disease which has similar manifestations to DIL, is SLE ( Systematic Lupus Erythematosus ), also autoimmune and you don't need any drug to trigger it. But it is not called ' Non drug lupus 'in any way.
Please feel free to discuss further,
Regards.


Patient replied :

Are fibro and cfs the main diseases that would have similar long term symptomology to sle


Hello,
You are right about the fibromyalgia and CFS part. Their symptoms are pretty much similar with similar causes.
Mostly the patients will have muscle pain, fatigue, memory issues, lack of concentration, e.t.c in CFS/ Fibromyalgia, with elevated CK levels.
When it comes to SLE though, the patients will have extensive symptoms, mostly affecting all the organ systems and even muscles. When it comes to muscles the patients will have fatigue and myalgia all day, but these symptoms are overshadowed by dermatological symptoms such as rashes, vasculitis, purpura, and other organ system symptoms such as chest pain, breathlessness, due to myocarditis, pleural effusion, then the classical butterfly malar rush on the face, e.t.c
Rather drug induced lupus mimics SLE in a lot of different levels.
Let me know if you have other queries,
Regards.


Dr. Jaydeep Tripathy
Category: HIV- AIDS Specialist
Experience: 
MBBS from Sri Ramachandra University in December 2011
M.Med (Family Medicine) - TNMGR University, Chennai
MBA-MPH in Public Health in March 2016, SRM University
Finished AFIH in March 2016, SRM University
MRCP ( UK ), Internal Medicine, Royal College of Physicians, June 2016
Fellowship in Diabetology from Martin Luther University in January 2017

Currently Resident Physician, in MD Radiodiagnosis - Kamakshi Memorial Hospital, Chennai
Dr. Jaydeep Tripathy and 4 other Medical Specialists are ready to help you

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