Hello
Thanks for your query at DoctorSpring.com.
I have gone through your question in detail and I can understand what you are going through.
Statistically and evidence wise, what you say is true. If a person doesn't improve on two different antidepressants given for adequate duration with adequate dosages, the illness is known as a resistant depression. The chances of improving the resistant depression are less but not impossible.
Further let me tell you that recent research has clearly shown that none of the antidepressants is more effective than the other and all are almost the same. Some patients respond well to some while others respond well to the other. So there is a good reason why you should seriously consider taking Celexa.
Further, the best treatment for resistant depression is a modified electroconvulsive therapy which is still very routinely used in many countries. You should discuss this option with your doctor and give it a serious thought.
Do let me know if you have any other doubts,
Kind regards
Dr. Srikanth Reddy MD