Main question: Are you saying that the 2 minimal uptake foci in my right femur are background activiity, and not to be worrried about? Or are they specific lesions with abnormality and asymmetry to be evaluated?? I am hoping that you mean that they are background noise, because that would calm my fears.

I did have a totally negative bone scan 3 months after the one with the foci. I just don't trust it, because it didn't show the arthritis in my knee either, so I think it just wasn't showing anything. (the first bone scan also showed arthritis in the knee--but the foci were too far up the femur to be connected to the arthritis. also the 2 foci were probably 6 inches apart). I am currently having radiation, and will be rescanned after that is over.

I probably shouldn't have bothered you about this again, because last time you said you weren't worried about those 2 spots at all, but now you sound worried. (you have the bone scan I sent you last time)

no mri or ct of that area (well, the ct/pet cut off somewhere in the femur--and the pet was negative--it may have included one of the foci--but the report said nothing about it)

1. I thought you were telling me that minimal uptake foci were background activity, is that true? And that to be cancer it had to be significant uptake. I was just wondering if people with just 2 foci can call it background activity???

2. The other question, is would those areas have hurt back when the scan was taken, if they were mets??

3. The reason I don't trust the 2nd (negative) bone scan is because it didn't show my arthritis in the knee, either (which had been on the other scan). Is that a reason to NOT trust the scan?

4. I've heard that bone scans on lobular cancer give false negatives 30 percent of the time. Is that true?

So, do you agree with your previous answer that for a bone scan to be positive you need significant uptake? And for it to be negative it can be minimal of no uptake? You said you were not worried at all about my scan.

Then I wouldn't have to worry.