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Frequent symptomatic ARRHYTHMIA with normal MRI, CATH,ECHO.

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I am a 64 year old white male in good overall health, normal blood pressure, weight, blood work and was on no regular medications. I had a cardiac ablation for pvc and nsvt 2 weeks ago at a university hospital due to frequent symptomatic arrhythmias that I have probably had since youth and were documented recently on a linc monitor. There have been cardiac MRI, cath, echo, stress echo, blood work, ekgs and so on to rule out structural disease and there was nothing significant revealed.

The procedure went well without complications. I was put on 20 mg Xarelto for 4 weeks and a low dose beta blocker. The blood thinner was prescribed to prevent the recurrence of a DVT of the right leg suffered 4 years old patientago. My question has to do with the sudden onset of a toothache that most likely will need treatment sooner rather than later. I will visit the dentist tomorrow and am not sure what will be found but I suspect an infection of some sort under a molar cap. I have had significant dental work in the past including 2 healing implants. I suspect that the dentist will have to consult with the electrophysiologist about treatment. However, my question has to do with what antibiotics can safely be administered concurrently with the Xarelto and if dental work can be done safely just 2 or 3 weeks after an ablation has been performed. I am assuming there is a small scar in the heart after ablation and this may pose a risk for infection. Additionally, I am allergic to Penicillin and all cephlasporins so my antibiotics usually given when needed are clindamycin or doxycycline.

So my questions have to do with what antibiotics can be given while on Xarelto given my allergy history and will the dental treatment have to be postponed until the blood thinner is stopped. And can important dental work be done 2 or 3 weeks after an ablation. Ablation was in the ventricle.

Category: Cardiologist

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Category: Internal Medicine Specialist
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Hello,
Thank you for your query at DoctorSpring.com
I have gone through the case history. Since Xarelto is a blood thinner , it needs to be stopped for your dental work if the dentist feels there will be some amount of bleeding involved with the dental procedure. Ideally it has to be stopped 4 to 5 days prior to planned procedure and restarted once the bleeding from the dental procedure is completed stopped.
The following medicines are found to be interacting with the action of Xarelto and increase bleeding , so you have to inform the physician if any of the underlying drugs you are taking

  • Ketoconazole (Nizoral)
  • Itraconazole (Onmel™, Sporanox)
  • Ritonavir (Norvir)
  • Lopinavir/ritonavir (Kaletra)
  • Indinavir (Crixivan)
  • Carbamazepine (Carbatrol, Equetro, Tegretol, Tegretol-XR, Teril™, Epitol)
  • Phenytoin (Dilantin-125, Dilantin)
  • Phenobarbital (Solfoton)
  • Rifampin (Rifater, Rifamate, Rimactane, Rifadin)
The antibiotics which you are usually given like Doxycycline and Clindamycin are not contraindicated.
As you have undergone Ablation for the PSVT , there is no contraindication for the dental procedure , as long as you the blood thinner 4 to 5 days prior to the dental procedure and another safe thing to be pretty sure , do venous doppler of right leg to see any evidence of Deep Vein Thrombosis.
I hope this information has cleared your doubts and you can contact me in case of any other doubts.
Regards
Dr Satish


Patient replied :

History: No diabetes, only antibiotic allergy, no hypertension, past hernia surgery no smoking ever, no drinking.
Is there a danger of infection to the ablation scar inside the heart from the suddenly impacted tooth as it has only been 2 weeks sinec the ablation procedure and could warfarin be substituted for the xarelto with inr checked. thanks for your replies


1) There is no danger of infection from the impacted tooth to the ablation scar .
2) Since Warfarin and Xarelto have same function , substituting will not help. In case Venous Doppler shows no evidence of Deep Vein Thrombosis then he safely stop 4 to 5 days prior to planned procedure.
Regards
Dr Satish


Dr. E. Satish Kumar
Category: Internal Medicine Specialist
Experience: 
Fellowship, Cardiology - Tamil Nadu Doctor M.G.R. Medical University - DNB, Cardiology, 2002 – 2005Training in Germany in Complicated AngioplastiesMedical School - Maharaja Krushna Chandra Gajapati Medical college, MBBBS MD, Int Medicine, 1989 – 1999.
Trained in Rota Abalation for treating Calcific coronary artery disease in Japan
Dr. E. Satish Kumar and 4 other Medical Specialists are ready to help you

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