Food or supplement to counteract SOCS

Resolved question:
Hi

My question is purely out of curiosity. I do not suffer from any disease but it is however of interest to me.

What food/supplements can be used to counteract the effect of SOCS (Suppressor of Cytoking Signalling, SOCS-2 in particular) as it is a protein that is involved in the negative feedback loop which attenuates GH and IGF-1 signalling via the inhibition of the JAK/STAT pathway.

I know that high levels of free fatty acids (accumulated from the effect of GH breaking down lipids) creates a negative growth hormone response, perhaps from the increased level of induced insulin response, but that may work via a separate mecahnism, I'm more interested in SOCS suppression.

Your response would be greatly appreciated.

Thanks

Submitted: 4 Days
Category: Family Physician-GP

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