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Depression, low libido, irritability on CLOMIPHENE CITRATE.

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I'm a 32 year old fit, active male, non-smoker, vegan, 5'10", 165lbs. Libido was almost nonexistent, low drive for anything (work, life, etc) depression, irritability, foggy mind, inability to put on muscle mass, etc. So I went and had blood work done. Have suffered from low T (WAS in the low 200's), have been taking 50mg of Clomiphene Citrate for the last couple of years and my T level is now in the high 700's, which is great. However, the other symptoms still persist. Libido is still nonexistent - being one of the main problems. Had been seeing an endocrinologist before I moved, and he was stumped as to why my libido was still low, given the rise in my numbers. I took it upon myself to go and get a full hormonal blood work done, got the results back, and they seem alarming. Want help deciphering the lab report and the best course of action to take.

Category: Endocrinologist

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Dr. J Muthukrishnan
Category: Diabetologist
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 21 Doctors Online

Expert:  Dr. J Muthukrishnan
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Hello,
Thank you for your query at DoctorSpring.com
I understand your concern.
From your reports, your testosterone levels have normalised but the LH FSH are higher a bit and so is estradiol, which can happen with clomiphene. TSH is slightly increased but doesnt require treatment at this stage. You need to stop clomiphene and watch for testosterone levels. if they fall, you can take testosterone gel or depot injections for better response on libido. You also may need counselling if all hormones fall into place and you still have low libido.
Feel free to discuss further,
Regards.

Dr. J Muthukrishnan
Category: Diabetologist
Experience: 
Fellowships/Training: 
1. 10th Asia-Pacific Pediatric Endocrine Society  Fellows meeting, Seoul, Korea, Oct 2008
2. Eighth ICMR Course on Genetics and Genetic Counseling – Jul 2008 – SGPGI, Lucknow
3. Annual Certificate Course on Endocrinological Laboratory Techniques at National Institute of Nutrition (ICMR) Hyderabad,India, ( Aug-Sep 2006) 
Fellowship: Endocrinology, Diplomate of National Board, National Academy of Medical Sciences, New Delhi, 2008, Medwin Hospital, Hyderabad
Senior Residency: Diplomate of National Board (General Medicine), National Academy of Medical Sciences, New Delhi, 2002
Residency: MD, General Medicine, 1997-2000, Armed Forces Medical College, 2nd position in University
Medical School: MBBS, Armed Forces Medical College, 1992
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