Hello,
Rash can be due to allergic reaction or infection. Recurring whole body rash with itching, like in your son's case, can be an allergic reaction. Anti histamines can symptomatically treat rash but, without knowing the cause the rash will recur once again when the child comes in contact with whatever is causing the rash.
Contact dermatitis due to any irritant substances, soaps, detergents used for cleaning clothes beddings etc can cause rash over the area of contact in some cases spread to whole body. Removal of the offending agent from contact of the child will be enough to prevent the rash from occurring. Atopic dermatitis can run in families and is associated with hay fever and allergic asthma. Check if any family members have history of asthma or hay fever. In photodermatitis exposure to light can cause rash over skin but it is usually limited to light exposed parts.
Whole body rash can be due to food allergy or medications. Try to recollect any change of food products given to your son before the rash started. As he is suffering from epilepsy, he must be on anti epileptic medications. Anti-epileptics like Phenytoin, Carbamezapine and Lamotrigine can cause allergic rash in some patients. Check if there is any recent change in his medications and report to doctor for switching to an alternate drug.
Proper diagnosis can be made once you take him to dermatologist. Thank you. Do get back to me if you have any other queries.