Helped Over 500,000 patients with 98%+ satisfaction.

Connect & Get Personalized 1-to-1 Answers from Expert Doctors

DoctorSpring > Question Home

Can pregnancy create unwanted ANTIBODIES complicating lung transplant?

Resolved Question:

I have a question about antibodies. I am awaiting a lung transplant and recently went off the pill for the first time in years. Surprisingly, I am still having sex with my boyfriend, but have been really really nervous about becoming pregnant. My main concern for getting pregnant is not just the obvious -- i would have to terminate the pregnancy, and its an all around bad situation for me right now -- but PRIMARILY i am concerned that I would develop antibodies that would then make me a more difficult match for transplant. I realized I don't understand enough about antibodies and pregnancy, and therein lies my question. 1- do all women develop antibodies from pregnancy? 2 - do the antibodies develop as a result of birth (mixing of fluids at that time)...or later in the pregnancy stage while the baby is still in the womb, or can it happen early on?

Basically I would like to know for peace of mind, even though it is unlikely, if, WORST CASE scenario, if i got pregnant and had to terminate the pregnancy early on...would I be at risk for developing antibodies that early? Or from the termination?

I should note that I had to terminate a pregnancy when i was younger (19) and never developed antibodies then.

I am very careful and use condoms + spermicide and all of that, but this is just me laying awake at night, worrying. Thank you .

Category: OBGYN

Ask Your Own Question

Category: Infertility Specialist
 27 Doctors Online

Hello.
Thanks for writing to DoctorSpring.com with your health concern.
The baby ( fetus ) is essentially a foreign body, because half the genetic composition of the baby is different from you , coming from the father.
Theoretically , each conception increases the chances of a mismatch in organ transplant, because each time you are sensitized to the foreign body that is the new baby.
However, most such sensitization occurs when blood from the baby passes into the mother's circulation.
For one, this is possible only after the placenta starts functioning, which is after 12 - 14 weeks of pregnancy.
So early trimester terminations are much less likely to immunize you with antibodies compared to full term pregnancies.
The risk is maximum during birthing, due to blood mixing at that time, and lesser during the last trimester of pregnancies, least in the first trimester, when the placenta is yet to take over.
Avoiding pregnancy is your best bet, and you are doing your best.
Termination itself leads to mild mixing of fluids, so it is better avoided.
However, in case you do conceive by accident, a first trimester termination is very less likely to load you with antibodies.
All the best, hope the answer helped you.
Please feel free to discuss further.


Dr. Aarti Vazirani
Category: Infertility Specialist
Experience: 
Residency: Obstetrics & Gynecolog, BJMC,Civil hospital, Ahmedabad, 2008
Post Graduate: MS (Obstetrics & Gynecology), B.J. Medical College, Ahmedabad, 2008
Medical School: MBBS, B.J. Medical College, Ahmedabad, 2004
Dr. Aarti Vazirani and 4 other Medical Specialists are ready to help you

Users who read this, also read:

Make informed and better medical decisions.

Join the 500,000 people who found a smarter, quicker way to get Answers, Recommendations & Expert Opinions.

Expert Doctors at fingertips

Recommendation on next step. Second-opinion.Multi-specialty.

Save Time

Average time for answers: 6 hours.

Save Money

$35 for typical specialist consult vs. $120 for a local appointment.

Free Follow-ups

Clarify, ask further questions for free in private conversation.

100% Satisfaction

Money back guarantee for the 1st reply. MEDNET Quality Board.

Start My Consultation

CHAT NOW

About DoctorSpring.com

Doctor Spring is a novel online Doctor consultation platform where you can get your medical questions answered by leading Doctors. Just Submit your question and rest assured that you will consult a Doctor easily. Once you submit the question, the Doctor from the concerned specialty will reply within hours. You can always ask more questions or add details with follow-up question options and make it an online doctor chat. You may use this service to consult a specialty or for getting medical second opinion. All paid services come with a MEDNET quality assurance and 100% money back guarantee.

DoctorSpring in news