Dear Sir,
My sincere aplogies for not closing this question. I need your support further. I am observing my mother condition and would like to bring to your notice. Please bear with me for few days.
After stopping trihexyphenidyl 10 days back, her delerium condition (short term memory problems and confusion) seems to be improving(betterment). Her Speech also improved a little. The ability to hold glasses and spoons is normal. Her external tremor is completely eliminated.
Her internal tremor which used to subside by use of propranolol also disappeared completely after stopping usage of Glipizide 2.5 mg, which she used to take during night along with Glyciphage SR (metformin hydrochloride SR). After understanding the possibility of tremor due to Glipizide, I stopped administering her with Glipizide and for the past four days(exactly the next day after stopping it) internal tremor got eliminated. Earlier she used to report internal tremor around 1-2 hours before administering Propranolol and she used to get complete relief from internal tremor 15min after taking propranolol. But after stopping Glipizide, even few more hours delay on administering Propranolol has not resulted in internal tremor.
Wether my observation, that is Glipizide may be the cause of tremor is reasonable ?
Her condition prompts me to continue without medication for few more weeks.
Kindly review the situation.
Once again I am extremely sorry for delay in closing this question.
Sir, I need your support.

Thanking you,
V.Gopi Krishna

Dear Sir, My mother's external tremor was completely eliminated, restlessness(internal tremor) was also absent for the past 15 days, even when propranolol was administerd 20 mg every alternate day, I am trying to slowly stop propranolol. Her speech also improved. But she still has short term memory problems but the condition is mcuh better than the days when she was taking trihexyphenidyl. The present condition is, she looks and feels tired, weak and drowsy,(inspite of her drowsiness she is not able to sleep during day time) this weakness seems to be gradually decreasing (she is becoming better). During moning, till breakfast and in the evening she looks more tired. When she is active, her speech is good and memory also a lot better. When she is weak, the speech quality goes down as well as memory. She complained about double vision (horizontal) thrice, all the times it disappeared with in a minute or two. is this part of EPS or PD.
She used to take rabeprazole 20 mg every morning and she was comfortable with her gastric troubles till she stopped trihexyphenidyl. The gastric problem resurfaced after stopping it. However, we stopped rabeprazole 20 mg 4 days ago and switched to Zandu Pancharista(ayurvedic preparation) and it is helping in a better way. Now apart from thyroid medication and Glyciphage SR (metformin hydrochloride SR), she is taking Propranolol 20 mg every alternate day. Shall we continue further with out further medication for few more weeks ? With elimination of tremor and improved speech, can we conclude that my mother doesn't have Primary parkinsionism and what she had is onlya drug induced parkinsonism ? OR Can the eliminated/reduced symptoms may resurface after few weeks, when trihexyphenidyl is flushed out.? Is her memory problem a part of ParkinsonsDisease ? or delirium induced by trihexyphenidyl ? (my observation is that she had such symptoms after starting trihexyphenidyl - is this coincidence ?). Please guide me Sir. Sir, I also uploaded her MRI scan reports. I ignored her spondylosis condition as to minimise the effects of drugs prescribed for it and want to take it up later if it is really problamatic. Thanks & Regards Gopi Krishna