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Need for METFORMIN to conceive with regular menstrual cycle.

Resolved Question:

My basic question is...if you have regular menstrual cycles, is there any need to prescribe metformin when trying to conceive? If metformin is prescribed for someone with regular cycles, can it make their cycles irregular?

Brief history:
Three years ago I had trouble conceiving. I was given a pcos diagnosis (because my cycles were about 35 days and I had the "swiss cheese" looking ovaries) and was treated with metformin and clomid which went fine. I became pregnant in a couple of months, but suffered a miscarriage a few months later. A few months after that I became pregnant while just taking metformin. I kept taking metformin until 5 months into pregnancy as well as crinone because I had a progesterone deficiency. I had my son in May of 2013 and he is healthy and happy!

I breast fed for a year and did not have a period during this time. When I stopped breasfeeding I immediately started having regular menstrual cycles...typically 26-31 days in length. I also started getting the "fertile mucus" more noticably.

I had regular cycles for 5 or 6 months. When my husband and I decided to try to conceive again (I'm now 38), I went to my ob gyn and she told me that even though all of my recent bloodwork/hormone levels and ultrasound showed that I was ovulating, that she thought I should still start taking metformin.

I started taking it and all of a sudden I went from normal cycles to starting to spot on the day I should be ovulating. The spotting lasted for 10 days. My ob gyn said that my hormone levels said I was starting a new cycle already! She started me on clomid to get my hormones going again (after the 10 days of bleeding).

After the clomid, I started spotting on day 15 of my cycle again!

Could this be caused by the metformin? She has me on 2 x 750mg a day. The only other thing I do is acupuncture for fertility (which I did with my pregnancy as well).

Could metformin be causing these strange, short cycles? I'm not sure why I need to take it if I have been having normal cycles since my son was born.

Thank you so much for your second opinion on this!
Krista

Category: Family Physician-GP

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Category: HIV- AIDS Specialist
 23 Doctors Online

Hello,
Thank you for your query at DoctorSpring.com
I totally understand your anxiety.
But I assure you, since you used a condom you have nothing to worry about.
With a condom on, it is 99 % effective in preventing any kind of STIs during unprotectd intercourse. And against oral sex it is even higher, since there is no contact with vaginal fluids.
If you had no condom on, then the chances of getting herpes would have been probable.
However you have nothing to worry.
Please enjoy your new year day!!
Regards.


Patient replied :

Actually I am struggling with anxiety, in fact I am on laxapro and lemectal. I want to be sure. When should I go to get tested. And what kind of tests should I ask for. I am so worried. I have always chosen to obstane.


Hello,
Thank you for the follow up.
You can get yourself tested within a week of the exposure.
You can get yourself evaluated for Herpes, HPV.
No other STI is possible through your exposure.
But I can guarantee it will be negative.
Regards.


Patient replied :

What about Hiv if this is my only sexual experiance.


Hello,
If this is your only sexual experience then you have no reason to be worried about HIV.
Regards.


Dr. Jaydeep Tripathy
Category: HIV- AIDS Specialist
Experience: 
MBBS from Sri Ramachandra University in December 2011
M.Med (Family Medicine) - TNMGR University, Chennai
MBA-MPH in Public Health in March 2016, SRM University
Finished AFIH in March 2016, SRM University
MRCP ( UK ), Internal Medicine, Royal College of Physicians, June 2016
Fellowship in Diabetology from Martin Luther University in January 2017

Currently Resident Physician, in MD Radiodiagnosis - Kamakshi Memorial Hospital, Chennai
Dr. Jaydeep Tripathy and 4 other Medical Specialists are ready to help you

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