This question regards my 15 year old daughter.

She is in good health with no major problems but she has been struggling with increasing depression over the past few months. We've taken her to a psychiatrist and he ordered some bloodwork. Specifically, the psychiatrist was looking for the MTHFR mutation. The test came back positive for this mutation, and the psychiatrist prescribed Delpin (15g), which should be delivered to us any day now.

I am seeking your input now because the labwork gives stern warning, not about depression, but about coronary disease. Quoting from the labwork:
"One copy of each of the MTHFR gene mutations tested, C677T and A1298C, was detected. The mutations are rarely found on the same chromosome; thus, this genotype is predicted to be associated with a poor metabolizer phenotype characterized by increase plasma homocysteine levels. This individual is at an increased risk for arteriosclerotic coronary disease and venous thrombosis as well as for toxicity from medications affecting folate metabolism."

Our focus thus far has been on her depression but I realize that this coronary issue needs to be
taken under advisement as well. My question for you is this: Are there any measures we can, and should take right now, at age 15, to address the lab report's warning? I understand that the problem here is her body's inability to process folic acid into folate. Delpin will provide mega doses of methylfolate which the psychiatrist hopes will balance her biochemestry and thus stabilize her mood. Will Delpin also be of benefit to the potential heart issue? Is there anything else she should consider taking? I've also be reading about a condition called homocystinuria and wonder if this is something she should be tested for. Otherwise, at what age would you recommen she start seeing a cardiologist?

Thank you for any information you can provide.
Derek Chambers