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How do body detoxify NEURON TOXICANTS?

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Thanks for your answer.
this will be the last questions for metal related toxification.
pls. teach me what is wrong in my thought.

if new developed neuron toxicant (high lipid soluble) gets into cells or neurons, not doing directly prohibiting some function (such as blocking receptors or enzyme or attack RNA or etc --> absoultly could make directly bad syptom in human) but it is only get into and stay...and could not be detoxified for a long time, after time flow cells feel very tired of becuase of toxicant staying in cell and cell graudually lose their function and 3-4month later cell is going to die and people die.

pls. explain me why this is not rational thinking.Becuase I don't know the biology.
(for example, if toxicant have no function to block receptor or enzyme...they could not get into and only staying in cell is not possible...)
Thank you very much.

Category: Allergy and Immunologist

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Category: HIV- AIDS Specialist
 31 Doctors Online

Hello,
Thank you for your query at DoctorSpring.com
I appreciate your interest in this topic.
However see if it can get inside the cell, by competing with receptors or whatever, it will mostly end up killing the cells. ( mercury comepting with selenium, killing the neurons ).
If it can't do that it will be biotransformed either by liver, or keep causing systemic toxicity.
It will affect the organs directly.
Only staying in cell is not possible, because once it goes inside it will change the physiological functions of the cells. Whenever other leucocytes realise the cell is not normal, the cell will be killed immediately.
Regards.


Dr. Jaydeep Tripathy
Category: HIV- AIDS Specialist
Experience: 
MBBS from Sri Ramachandra University in December 2011
M.Med (Family Medicine) - TNMGR University, Chennai
MBA-MPH in Public Health in March 2016, SRM University
Finished AFIH in March 2016, SRM University
MRCP ( UK ), Internal Medicine, Royal College of Physicians, June 2016
Fellowship in Diabetology from Martin Luther University in January 2017

Currently Resident Physician, in MD Radiodiagnosis - Kamakshi Memorial Hospital, Chennai
Dr. Jaydeep Tripathy and 4 other Medical Specialists are ready to help you

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