Helped Over 500,000 patients with 98%+ satisfaction.

Connect & Get Personalized 1-to-1 Answers from Expert Doctors

DoctorSpring > Question Home

Gained lot of weight, increased anxiety on EFFEXOR.

Resolved Question:

Hi,
I suffer from severe GAD. Going back years ago, I was on Paxil for 12 years and it worked great, except I gained a lot of weight. So I went off of it five years ago. Within the past five years I have been on Zoloft (1.5 years), Lexapro (l0 mgs) 1.5 years both worked great and then they lost their efficacy. 

Then last year, I had a bad knee injury and could not get my dr, as he was away. I was on Lexapro at the time, but it lost its efficacy. I went to a nurse prac. who prescribed me Effexor XR 112 mgs (yes 75 mg tablet and 37.5 table). She said most people went into remission from it forever. Well, I was fine for 6 months and then had to have knee surgery.  Six weeks after the surgery, I got my anxiety back again. Seriously, I never missed a dose of effexor xr. Well I ended up not going back to the nurse but to my regular doctor  who upped the dose of effexor xr to 225 mgs. After two weeks I had to go off of Effexor,  because my blood pressure skyrocketed. He tapered me off of Effexor to Prozac gradually, which was good.

Now I am off the Effexor totally (tappered off by dr. with Prosac) I have been on Prozac 20 mgs for 3 weeks and still feel horrible. I am so upset. I am just hoping the Prozac will work.  I know it has nothing to do with the Effexor.  I have to work, have a mortgage, etc. Do you think because I was on Effexor, being such a strong drug, that Prozac, won't work. Also, I am now getting Cog. Behavior Therapy.  I am so worried that I will keep getting this. Please any information you could give me I would soooo appreciate. Thank you.

Category: Psychiatrist

Ask Your Own Question

 32 Doctors Online

Hello
Thanks for posting your query at DoctorSpring.com
I have gone through your question in detail and I can understand what you are going through.
Among the various antidepressants and anti-anxiety medicines, one of them is superior to any one. Some medicines may act well one some and may fail to act on another. The medicines are decided based on the tolerability and acceptability of side-effects. If you have already tried venlafaxine, even then fluoxetine may work for you. Even if fluoxetine doesnt work for you then there are other medicines like desvenlafaxine, mirtazapine or agomelatine which can still work for you. Resistant anxiety disorders may even benefit with kitamine infusion which is a new therapy for resistant anxiety and depression. Further you are already undergoing CBT and this is very effective for anxiety disorder but will take time. have patience and tings will be better.
Hope this helps,
In case if you have any further query, do let me know.
Kind regards
Dr. Srikanth Reddy


Patient replied :

Hi, Thank you. I cannot take SNRI as they raise my blood pressure so high. How long will it take for the Prozac to work. Would it work quicker if dr upped dose. Are there any other SSRIs that are new or may work? Thank you.


Hello
Not all SNRI raise the blood pressure. Venlafaxine is notorious for the rise in blood pressure. Still other medicines like mirtazapine and desvenlafaxine can help in reducing the anxiety without increasing the blood pressure. Further some old medications like clomipramine or imipramine can also be tried if the modern medicines are not helping you much. As of now until the new medicines start showing their effect, the symptoms can be controlled with propranolol or clonazepam as of now.
Hope this helps,
Kind regards
Dr. Srikanth Reddy MD


Patient replied :

How long does it take Prozac to kick in. I have been on 20 mgs for 3 weeks. Thank you


Hello
Normally the effects begin by 3-4 weeks. You may wait another one week and look for the effects.
Regards.


Dr. Srikanth Reddy
Category: Sexologist
Experience: 
Doctor of Medicine (MD), Psychiatry Residency Program,2001 – 2012
M.B.B.S,Mahatma Gandhi Institute Of Medical Sciences, Sevagram

Certificate Course in sex Therapy and Counselling, Sexology and Counselling, A
Sexology,Medikon Sexual Sciences, Mumbai

Training in Advanced Neurology at a leading corporate hospital (CARE hospital) in Hyderabad

Child Psychiatry Training in National Institute of Mental Health and Neuro-Sciences, Bangalore

Sex Therapy and Counsellingat MEDIKON Sexual Sciences, Mumbai.
Dr. Srikanth Reddy and 4 other Medical Specialists are ready to help you

Users who read this, also read:

Make informed and better medical decisions.

Join the 500,000 people who found a smarter, quicker way to get Answers, Recommendations & Expert Opinions.

Expert Doctors at fingertips

Recommendation on next step. Second-opinion.Multi-specialty.

Save Time

Average time for answers: 6 hours.

Save Money

$35 for typical specialist consult vs. $120 for a local appointment.

Free Follow-ups

Clarify, ask further questions for free in private conversation.

100% Satisfaction

Money back guarantee for the 1st reply. MEDNET Quality Board.

Start My Consultation

CHAT NOW

About DoctorSpring.com

Doctor Spring is a novel online Doctor consultation platform where you can get your medical questions answered by leading Doctors. Just Submit your question and rest assured that you will consult a Doctor easily. Once you submit the question, the Doctor from the concerned specialty will reply within hours. You can always ask more questions or add details with follow-up question options and make it an online doctor chat. You may use this service to consult a specialty or for getting medical second opinion. All paid services come with a MEDNET quality assurance and 100% money back guarantee.

DoctorSpring in news