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Elevated cpk levels may result from hypothyroidism. Even elevated ck mb fraction can result from hypothyroidism. Trop I is far more sensitive and specific. What is the patient admitted for?
In case of chest pain if negative trop s to 12 hours after pain onset means that myocardial infarction has not occured. In that case patient may undergo a stress test 48 hours after pain subsides and if normal doesn't need to undergo an angiography.
Feel free to discuss further,
Regards
Dr Vivek Mahajan
DM Cardiology